Cognitive profiles in epilepsy are as
heterogenous as the epileptic syndromes themselves; causes, topography of
epileptogenic areas, pathogenetic mechanisms, and the diverse features
characterising the clinical course all contribute to the effect on cognition.
Chronic epilepsy generally impairs cognition, but it also induces processes of
functional reorganisation and behavioural compensation. In most idiopathic
epilepsies, cognition is only mildly deteriorated or even normal by clinical
standards. Localisation-related cryptogenic and symptomatic epilepsy disorders
are accompanied by focal deficits that mirror the specific functions of the
respective areas. Poor cognitive outcome is generally associated with an early
onset and a long duration of the disease and with poor seizure control. There
is evidence that cognitive functions are already impaired at the onset of the
disease, and that the maturation of cognitive functions in children is
susceptible to the adverse influence of epilepsy. In adults, cognitive decline
progresses very slowly over decades with an age regression similar to that of
people without epilepsy. Successful epilepsy surgery can stop or partly reverse
the unfavourable cognitive development, but left-temporal resections in
particular have a high risk of additional postoperative verbal memory
impairment. Cognitive recovery in the adult brain after successful surgery
indicates functional compensation and, to some degree, functional reorganisation
or a reactivation of functions previously suppressed by influence from distant
but connected epileptogenic areas.
Based on forepassed research and clinical
experience and statistics, we think that stem cell treatment is able to treat
epilepsy and recover the patient’s cognitive ability partly.
Key words:
epilepsy, cognitive, impair, recovery
Description: The
stem cell treatment is able to treat epilepsy and recover the patient’s
cognitive ability partly.
